Finally the female subjects are included in the biomedical research

June 28, 2020

The death rate for men is double than that of women, though the likelihood of contracting Covid-19 is almost equal.


Biomedical studies has been under mainstream male domination. Traditionally medical subjects have only been males. Female subjects were overlooked until the past decade. It's not obligatory that each rarity in a human body will influence both the sexes equally.

In line with the statistics, only 28% of 800 medical surveys included both the sexes in 2009. Another 16% of studies didn't state which sex they used. The US National institutes of Health instituted Sex as a biological variable in 2016. The recent studies in 2019, inclusive of both men and women together escalated to 49%.

It is crucial to examine both the sexes. Primarily because of mismatched genetics. A malady and it's treatment can differ because of the dissimilar chromosomes. By conducting research on both the sexes, it can be revealed if a phenomenon is common for both. The basic thesis on a subject becomes irrelevant if all the available data isn't used. Thus, it's very important and logical to integrate sex in clinical research.


Alteration and distinct patterns might be observed while conducting research with both men and women. During 1997-2000 ten prescription drugs were pulled out of the market by US Food and Drug Administration (FDA). Eight out of ten drugs proved to be hazardous on women. Four of them were mainly prescribed to females but the other four had detrimental effects even though equally stipulated. Physiological differences and its clinical importance were disclosed thereupon.


After decades of medical research, the researchers realised the weight of inclusion of women in studies and the large differences among the sexes beyond the reproductive systems.

The significant sex bias was due to the knowledge that estrogen and progesterone produced in females might ruin the studies.


Presently it is revealed that these variations do not affect the research adversely. Instead it is a major factor for dissimilar results. Another vital issue is being one step ahead with the male data as they had been studied frequently in the past. So it isn't unusual to have a certain amount of proclivity towards male specimens. Then again, the data remains patchy.

With increasing knowledge and technology, it is time to adopt a better mindset which is beneficial for the people.


Thus, it is really important to notice and be aware whether the orthodox male bias is changing for betterment in the field of ailment.



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